Program – Tuesday, April 23
Session 1
Opening Session: The Renewed Global Agenda for Sepsis
Moderated by:
Louise Thwaites
Asia Pacific Sepsis Alliance, Vietnam
09:00h Berlin Time (CEST)
Opening Remarks
Louise Thwaites, Asia Pacific Sepsis Alliance, Vietnam
Opening Remarks
Niranjan 'Tex' Kissoon, Global Sepsis Alliance, Canada
Opening Remarks
Tedros Adhanom Ghebreyesus, Director-General World Health Organization, Switzerland
Opening Remarks
Ricardo Baptista Leite, UNITE Parlamentarians Network for Global Health, Portugal
Reinvigorating Global Action on Sepsis
Konrad Reinhart, Sepsis Stiftung, Germany
2030 Global Agenda for Sepsis | Framework
Mariam Jashi, Global Sepsis Alliance, Germany
Video Messages from Partner Organizations
David Ripin, Clinton Health Access Initiative (CHAI), United States of America
Subasree Srinivasan, Global Antibiotic Research & Development Partnership (GARDP), Switzerland
Eleanor Nwadinobi, Medical Women’s International Association (MWIA), Nigeria
Closing Remarks
Duncan Brown, Australia
Session 2
The Need for Early Diagnosis and Treatment of Sepsis in Surgical Patients
Moderated by:
Arthur Kwizera
Makerere University College of Health Sciences, Uganda
10:00h Berlin Time (CEST)
Surgical Patients, Multi-Organ Failure, and the SOFA Score
David Harrison, Intensive Care National Audit & Research Centre, United Kingdom
Where Are We with Electronic Sepsis Surveillance and Early Warning Tools?
Frédéric Michard, Michard Consulting, Switzerland
Source Control – When and How?
Jan De Waele, Ghent University Hospital, Belgium
Research Priorities for Sepsis and Septic Shock in Surgical Patients
Lena Napolitano, University of Michigan School of Medicine, United States of America
The Importance of Early Clinical Suspicion in the Diagnosis of Sepsis
Halden Scott, University of Colorado School of Medicine, United States of America
Session 3
Data, AI, and Predictive Modeling in Sepsis
Moderated by:
Peiling Yap
HealthAI, Switzerland
11:30h Berlin Time (CEST)
New Data Initiatives for Monitoring Sepsis Globally
Paul Turner, Madihol Oxford Tropical Medicine Research Unit, Cambodia
Data Partnerships: Leveraging Insights from Emerging Infections to Fight Sepsis
Laura Merson, ISARIC, University of Oxford, United Kingdom
Can AI Models Really Improve Sepsis Outcomes?
Paul Elbers, Amsterdam UMC, The Netherlands
Developing Equitable AI for Sepsis Prediction in Children
María del Pilar Arias, Dr. Ricardo Gutiérrez Children’s Hospital, Argentina
From the Research Lab to the Wards: Designing AI Systems for Patient Safety and Clinical Usability
Chris Paton, University of Otago, New Zealand
Session 4
How Does Hypervolemia Increase the Mortality Risk in Sepsis?
Moderated by:
Naomi Hammond
Asia Pacific Sepsis Alliance, Australia
13:00h Berlin Time (CEST)
Desired and Undesired Effects of Fluids
Manu Malbrain, International Fluid Academy, Poland
Diagnosis and Management of Hypervolemia in Sepsis
Sheila Myatra, Asia Pacific Sepsis Alliance, India
Can Early Use of Vasopressors Avoid Hypervolemia?
Jean-Louis Teboul, University Paris-Saclay, France
The Safety Limits to Stop Fluid Infusions
Ludhmila Hajjar, University of São Paulo, Brazil
Fluid Removal: When and How?
Marlies Ostermann, Guy’s and St Thomas’ NHS Foundation Trust, United Kingdom
Session 5
The Role of Biomarkers in the Early Detection of Sepsis
Moderated by:
Sophie Yacoub
Oxford University Clinical Research Unit, Vietnam
14:30h Berlin Time (CEST)
Biomarkers of Relevance in Low-Resource Settings
Andrew Argent, University of Capetown, South Africa
A Patient is Admitted at the Emergency: What to Do?
Rita Murri, Gemelli University of Rome, Italy
Clinical Phenotypes: What Do They Suggest?
Chris Seymour, University of Pittsburgh, United States of America
Biomarkers as Endpoints for Treatment Efficacy
Evangelos J. Giamarellos-Bourboulis, European Sepsis Alliance, Greece
Reducing Antibiotics With a Single Host Biomarker in Neonates Suspected of LOS: The Emeraude Study
Sylvie Pons, Joint Research Unit Hospices Civils de Lyon – bioMérieux, France
Session 6
Detecting Sepsis in the Ventilated Patient
Moderated by:
Antonio Artigas
Global Sepsis Alliance, Spain
16:00h Berlin Time (CEST)
New Global Definition of Acute Respiratory Distress Syndrome (ARDS)
Michael Matthay, University of California San Francisco, United States of America
Alveolar Inflammation in ARDS
Lieuwe Bos, Amsterdam UMC, The Netherlands
Biomarkers in ARDS and Sepsis
Lorraine Ware, Vanderbilt University, United States of America
Unraveling the Enigma of Genetics and Phenotypes in Sepsis and ARDS
Carmen Barbas, University of São Paulo, Brazil
Diagnosis of Ventilator-Associated Pneumonia
Pedro Povoa, University of Lisboa, Portugal
Ventilator Support and Sepsis in Low-Middle Income Countries
Marcus Schultz, Mahidol University, Thailand
Session 7
Closing the Needs in Pediatric Sepsis
Moderated by:
Brenda Morrow
University of Cape Town, South Africa
17:30h Berlin Time (CEST)
The Phoenix Criteria – How We Got Here
Luregn Schlapbach, University Children’s Hospital Zurich, Switzerland
The Phoenix Criteria Revealed
Daniela de Souza, Global Sepsis Alliance, Brazil
Personalized Care Post-Discharge for Sepsis
Matthew Wiens, University of British Columbia, Canada
The Latest Update on Fluid Therapy in Sepsis
Jhuma Sankar, All India Institute of Medical Sciences, India
The Advances of the WHO in Pediatric Sepsis Initiatives
Emilie Calvello-Hynes, World Health Organization, Switzerland
Empiric Treatment of Neonatal Sepsis: Progress to Date
Sally Ellis, Global Antibiotic Research & Development Partnership, Switzerland
Session 8
Personalized Approaches to Sepsis Management
Moderated by:
Maha Aljuaid
Eastern Mediterranean Sepsis Alliance, Saudi Arabia
19:00h Berlin Time (CEST)
TREM-1 Pathway
Bruno Francois, Dupuytren University Hospital, France
ARDS: Room for Precision Treatment?
Carolyn Calfee, University of California, San Francisco Medical Center, United States of America
Modulation of Complement
Alexander Vlaar, Amsterdam UMC, The Netherlands
Macrolides for Community-Acquired Pneumonia
Michael Niederman, Weill Cornell Medicine, United States of America
Reversal of Immunoparalysis
Sara Cajander, Örebro University, Hospital, Sweden
Session 9
Challenges and Solutions for Early Recognition and Treatment of Sepsis
Moderated by:
Eleanor Nwadinobi
Medical Women’s International Association, Nigeria
20:30h Berlin Time (CEST)
ARCS: Understanding Risk Factors for Delayed Presentation and Care of Sepsis Patients in DRC, Nigeria, and Sierra Leone
Patrick de Marie Katoto, Catholic University of Bukavu, DRC
Sepsis Check – A Preclinical Checklist for Early Detection and Education
Wiltrud Abels, Charité – Universitätsmedizin Berlin, Germany
Early Resuscitation of Septic Shock in the ED – Which Perfusion Parameters for Target Resuscitation?
Glenn Hernández Poblete, Pontifical Catholic University of Chile, Chile
Sepsis in Brazilian Emergency Departments: A Prospective Multicenter Observational Study
Flavia Machado, Latin American Sepsis Institute, Brazil
Smart Triage: Electronic Support for Early Recognition and Triage of Severely Ill Patients in Ugandan Emergency Departments
Mark Ansermino, BC Children’s Hospital, Canada
Closing Remarks
Michael Wong, Physician-Patient Alliance for Health & Safety, United States of America